A vaginal infection during the early months of pregnancies could prove disastrous. This prompts the consultation of an Ob-Gyn before it can do any damage to the mother and/or the baby inside her.

Bacterial Vaginosis during early pregnancy is especially dangerous because it is associated with an increased risk of preterm birth or if not, a baby with a low birth weight. Preterm premature rupture of membranes or the bag of water is also possible, making the mother and child at risk for other infections. Uterine infection after delivery may also result if the BV was left untreated during the pregnancy. And recent studies also show that there is a connection between BV and second-trimester miscarriage.

During pregnancy, most of the normal antibiotic treatments are contraindicated because majority of these drugs have teratogenic (alters the normal development) effects on the baby, especially during the early pregnancy when the vital organs are being formed.

Clindamycin and Metronidazole were found to be effective in treating BV during pregnancy without the teratogenic effects seen in other drugs. Oral clindamycin is given in a 300mg preparation while metronidazole is prepped in 500mg. Both drugs must be taken twice a day for seven days to complete the treatment.

Topical medications applied during bedtime for five days are effective for symptomatic relief but insufficient in preventing complications in pregnancy. A recent study shows that with antibiotic therapy, the occurrence of preterm premature rupture of membranes and low birth weight are greatly diminished. This however, did not find sufficient evidence that antibiotic therapy prevents premature labor.